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vivacell_graurotbuttonklein  Recent news

September 2016

Cooperation with Dhofar University (Sultanate of Oman)

 

May 2016

We were awarded the Stifterverband's "Innovative through Research" for our research activities.

 

April 2016

New Version of SimDerma including 30 important dermato-cosmetic parameters.

Read more here.

 

November 2015:

New Services in neurotoxicity and neuroprotection

Read more here.

 

October 2015:

SimDerma - new screening platform for cosmetic ingredients.

simderma_werbefoto

Read more here.

 

Services in Oral Care.

Read more here.

 

September 2015:

Please have a look at our new services in miRNA research.

Read more here.

 


 

New publications by VivaCell:

 

"Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary
microglia."

in J Neuroinflamm. 2016 Jan

 

"Antimalarial Drug Artemether Inhibits Neuroinflammation in BV2 Microglia
Through Nrf2-Dependent Mechanisms."

in Mol Neurobiol. 2015 Nov

 

"microRNA-26a modulates inflammatory response induced by toll-like receptor 4 stimulation in microglia."

in J Neurochem, 2015 Sep

 

"Anti-inflammatory effects of 5-HT3 receptor antagonists in interleukin-1beta stimulated primary human chondrocytes."
in Int Immunopharmacol. 2014 Jun

"Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia."
Neuroscience. 2014 Jan 28

 

 

Read more news...

 

 

vivacell_graurotbuttonklein  Opinions from our customers:

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Dr. G. Weiss (PASCOE pharmazeutische Praeparate GmbH):

:

"During our well going cooperation over several years, we learned to appreciate VivaCell as a reliable and competent co-operation partner in pre-clinical research. Therefore we are looking forward to continue our successful partnership."  

 

 

Read more
opinions...

 

 

Phytodrugs / Nutraceuticals
Immunology/Inflamm./AIDS
CNS
Cancer / Oncology
Metabolism
Chemistry
Aktuelle Publikationen

 

We are awarded for our R&D activities by the Stifterverband:

 

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We are proud members of:

 

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    koop-phyto-logo

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VivaCell Quality-Certificate:

 

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Die aktuellen Veröffentlichungen von VivaCell:

2016

Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary
microglia.
  (Link to download of full Free PMC Article)
de Oliveira AC, Yousif NM, Bhatia HS, Hermanek J, Huell M, Fiebich BL.
J Neuroinflammation. 2016 Jan 18;13:11. doi: 10.1186/s12974-015-0473-7.
PMID: 26780827 Free PMC Article

2015

Antimalarial Drug Artemether Inhibits Neuroinflammation in BV2 Microglia
Through Nrf2-Dependent Mechanisms.

Okorji UP, Velagapudi R, El-Bakoush A, Fiebich BL, Olajide OA.
Mol Neurobiol. 2015 Nov 25. [Epub ahead of print]
PMID: 26607631

 

microRNA-26a modulates inflammatory response induced by toll-like receptor 4 stimulation in microglia.
Kumar A, Bhatia HS, de Oliveira AC, Fiebich BL.
J Neurochem. 2015 Sep 16. doi: 10.1111/jnc.13364. [Epub ahead of print]

GABAA Receptor Binding Assays of Standardized Leonurus cardiaca and Leonurus japonicus Extracts as Well as Their Isolated Constituents.

Planta Med. 2015 Aug;81(12-13):1103-10. doi: 10.1055/s-0035-1546234.
Rauwald HW1, Savtschenko A1, Merten A1, Rusch C1, Appel K2, Kuchta K3.
[Epub ahead of print]

 

Chokeberry (Aronia melanocarpa (Michx.) Elliot) concentrate inhibits NF-KB and synergizes with selenium to inhibit the release of pro-inflammatory mediators in macrophages.

Fitoterapia. 2015 Sep;105:73-82. doi: 10.1016/j.fitote.2015.06.009.
Appel K1, Meiser P2, Millán E3, Collado JA3, Rose T1, Gras CC4, Carle R5, Muñoz E6.
[Epub ahead of print]

2014

Anti-inflammatory effects of 5-HT3 receptor antagonists in interleukin-1beta stimulated primary human chondrocytes.

Stratz C, Anakwue J, Bhatia H, Pitz S, Fiebich BL.

Int Immunopharmacol. 2014 Jun 26. pii: S1567-5769(14)00217-3. doi: 10.1016/j.intimp.2014.06.003. [Epub ahead of print] PMID: 24975660 Related citations

 

Picralima nitida seeds suppress PGE2 production by interfering with multiple signalling pathways in IL-1ß-stimulated SK-N-SH neuronal cells.

Olajide OA, Velagapudi R, Okorji UP, Sarker SD, Fiebich BL. J Ethnopharmacol. 2014 Jan 31. pii: S0378-8741(14)00074-9. doi: 10.1016/j.jep.2014.01.027. [Epub ahead of print] PMID: 24491645


 

Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia.

Singh V, Bhatia HS, Kumar A, de Oliveira AC, Fiebich BL. Neuroscience. 2014 Jan 28. pii: S0306-4522(14)00057-8. doi: 10.1016/j.neuroscience.2014.01.037. [Epub ahead of print] PMID: 24480366

2013

Controlled type II diabetes mellitus has no major influence on platelet micro-RNA expression. Results from micro-array profiling in a cohort of 60 patients.

Stratz C, Nührenberg T, Fiebich BL, Amann M, Kumar A, Binder H, Hoffmann I, Valina C, Hochholzer W, Trenk D, Neumann FJ., Thromb Haemost. 2013 Dec 19;111(5). [Epub ahead of print] PMID: 24352417

 

Inhibition of Neuroinflammation in LPS-Activated Microglia by Cryptolepine.

Olajide OA, Bhatia HS, de Oliveira AC, Wright CW, Fiebich BL.  Evid Based Complement Alternat Med. 2013;2013:459723. doi: 10.1155/2013/459723. Epub 2013 May 8. PMID: 23737832

 

Anti-neuroinflammatory properties of synthetic cryptolepine in human neuroblastoma cells: possible involvement of NF-?B and p38 MAPK inhibition.

Olajide OA, Bhatia HS, de Oliveira AC, Wright CW, Fiebich BL. Eur J Med Chem. 2013 May;63:333-9. doi: 10.1016/j.ejmech.2013.02.004. Epub 2013 Feb 19. PMID: 23507189

 

Mechanisms of anti-inflammatory property of Anacardium occidentale stem bark: inhibition of NF-KB and MAPK signalling in the microglia.
Olajide OA, Aderogba MA, Fiebich BL. J Ethnopharmacol. 2013 Jan 9;145(1):42-9. doi: 10.1016/j.jep.2012.10.031. Epub 2012 Nov 6.
PMID: 23142196  [PubMed - in process]

2012

 

Bridelia ferruginea Produces Antineuroinflammatory Activity through Inhibition of Nuclear Factor-kappa B and p38 MAPK Signalling 

Olajide OA, Aderogba MA, Okorji UP, Fiebich BL.

Evidence-Based Complementary and Alternative Medicine. Volume 2012 (2012),
Article ID 546873 [Open Access]

 

A Cannabigerol Quinone Alleviates Neuroinflammation in a Chronic Model of Multiple Sclerosis.
Granja AG, Carrillo-Salinas F, Pagani A, Gómez-Cañas M, Negri R, Navarrete C, Mecha M, Mestre L, Fiebich BL, Cantarero I, Calzado MA, Bellido ML, Fernandez-Ruiz J, Appendino G, Guaza C, Muñoz E
J Neuroimmune Pharmacol. 2012 Sep 14. [Epub ahead of print]

 

Role of prostaglandins in neuroinflammatory and neurodegenerative diseases.
Lima IV, Bastos LF, Limborço-Filho M, Fiebich BL, de Oliveira AC.
Mediators Inflamm. 2012;2012:946813. Epub 2012 Jun 18.   Free PMC Article

The anti-inflammatory effects of the 5-HT(3) receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes.

Stratz C, Bhatia HS, Akundi RS, Nührenberg T, Trenk D, Muñoz E, Fiebich BL.

Int Immunopharmacol. 2012 Aug;13(4):398-402. Epub 2012 Jun 1.

 

Micro-array profiling exhibits remarkable intra-individual stability of human platelet micro-RNA.

Stratz C, Nührenberg TG, Binder H, Valina CM, Trenk D, Hochholzer W, Neumann FJ, Fiebich BL.

Thromb Haemost. 2012 Apr;107(4):634-41. Epub 2012 Feb 28.

 

Molecular targets of the antiinflammatory Harpagophytum procumbens (devil's claw): inhibition of TNFa and COX-2 gene expression by preventing activation of AP-1.

Fiebich BL, Muñoz E, Rose T, Weiss G, McGregor GP.

Phytother Res. 2012 Jun;26(6):806-11. doi: 10.1002/ptr.3636. Epub 2011 Nov 10.

 

Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia.

de Oliveira AC, Candelario-Jalil E, Langbein J, Wendeburg L, Bhatia HS,

Schlachetzki JC, Biber K, Fiebich BL.

J Neuroinflammation. 2012 Jan 3;9:2.PMID:22214188[PubMed - in process]

 

 

 

 

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